Human TGFBI protein (Recombinant) (N-His) (STJP005458)

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STJP005458
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TGFBI-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TGFBI
Gene ID: 7045
Uniprot ID: BGH3_HUMAN
Immunogen Region: Gly423-Leu632
Immunogen: Homo sapiens (Human)
Post Translational Modifications Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.these residues may be required for binding to calcium. According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues. The EMI domain contains 2 expected intradomain disulfide bridges (Cys-49-Cys85 and Cys-84-Cys-97) and one unusual interdomain disulfide bridge to the second FAS1 domain (Cys-74-Cys-339). This arrangement violates the predicted disulfide bridge pattern of an EMI domain.
Function Plays a role in cell adhesion. May play a role in cell-collagen interactions.
Protein Name Transforming Growth Factor-Beta-Induced Protein Ig-H3
Beta Ig-H3
Kerato-Epithelin
Rgd-Containing Collagen-Associated Protein
Rgd-Cap
Database Links Reactome: R-HSA-977225
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
May Be Associated Both With Microfibrils And With The Cell Surface
Alternative Protein Names Transforming Growth Factor-Beta-Induced Protein Ig-H3 protein
Beta Ig-H3 protein
Kerato-Epithelin protein
Rgd-Containing Collagen-Associated Protein protein
Rgd-Cap protein
TGFBI protein
BIGH3 protein

Information sourced from Uniprot.org

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