• Human TFPI protein (Active Recombinant) (C-His) (STJP001426)
  • Human TFPI protein (Active Recombinant) (C-His) (STJP001426)
  • Human TFPI protein (Active Recombinant) (C-His) (STJP001426)
  • Human TFPI protein (Active Recombinant) (C-His) (STJP001426)

Human TFPI protein (Active Recombinant) (C-His) (STJP001426)

SKU:
STJP001426

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Active Recombinant-Human TFPI-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity: Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2. The IC50 value is
Gene Symbol: TFPI
Gene ID: 7035
Uniprot ID: TFPI1_HUMAN
Immunogen: Recombinant Human TFPI Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp29-Lys282) of human TFPI1 (Accession #NP_006278.1) fused with a 6×His tag at the C-terminus.
Post Translational Modifications O-glycosylated.
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Protein Name Tissue Factor Pathway Inhibitor
Tfpi
Extrinsic Pathway Inhibitor
Epi
Lipoprotein-Associated Coagulation Inhibitor
Laci
Database Links Reactome: R-HSA-140834
Cellular Localisation Isoform Alpha: Secreted
Isoform Beta: Microsome Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Tissue Factor Pathway Inhibitor protein
Tfpi protein
Extrinsic Pathway Inhibitor protein
Epi protein
Lipoprotein-Associated Coagulation Inhibitor protein
Laci protein
TFPI protein
LACI protein
TFPI1 protein

Information sourced from Uniprot.org

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