Human TFF1 (Trefoil Factor 1) Sandwich ELISA Kit (STJE0020115)
SPECIFICATIONS
General Information
| Short Description | This TFF1 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenate and other biological samples. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 75 pg/mL |
| Detection Limit | 125-8000 pg/mL |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Storage Instruction | If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
| Assay Time | 3.5H |
| Detection | Colorimetric |
Target Information
| Gene Symbol | TFF1 |
| Gene ID | 7031 |
| Uniprot ID | TFF1_HUMAN |
| Specificity | This kit recognizes human TFF1 in samples. No significant cross-reactivity or interference between human TFF1 and analogues was observed. |
| Sample Type | Serum, Plasma, Tissue homogenate and Other biological samples |
Additional Info
| Tissue Specificity | Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level). |
| Post Translational Modifications | |
| Function | Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. |
| Protein Name | Trefoil Factor 1Breast Cancer Estrogen-Inducible ProteinPnr-2Polypeptide P1.AHp1.AProtein Ps2 |
| Database Links | Reactome: R-HSA-9018519 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Trefoil Factor 1 ELISA kitBreast Cancer Estrogen-Inducible Protein ELISA kitPnr-2 ELISA kitPolypeptide P1.A ELISA kitHp1.A ELISA kitProtein Ps2 ELISA kitTFF1 ELISA kitBCEI ELISA kitPS2 ELISA kit |
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Information sourced from Uniprot.org