Human TESC protein (Recombinant) (N-His) (STJP008273)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TESC-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TESC |
| Gene ID | 54997 |
| Uniprot ID | CHP3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-His214 |
Additional Info
| Function | Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin. |
| Protein Name | Calcineurin B Homologous Protein 3TescalcinTsc |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmMembraneLipid-AnchorCell MembraneCell ProjectionLamellipodiumRuffle MembraneColocalizes With Slc9a1 At The Plasma Membrane |
| Alternative Protein Names | Calcineurin B Homologous Protein 3 proteinTescalcin proteinTsc proteinTESC proteinCHP3 protein |
Information sourced from Uniprot.org