Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human Tenascin-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNC |
Gene ID: |
3371 |
Uniprot ID: |
TENA_HUMAN |
Immunogen Region: |
Gly23-Ser621 |
Immunogen: |
Recombinant Human Tenascin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly23-Ser621) of human Tenascin (Accession #NP_002151.2) fused with a 6×His tag at the C-terminus. |
Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
Protein Name | TenascinTnCytotactinGmemGp 150-225Glioma-Associated-Extracellular Matrix AntigenHexabrachionJiMyotendinous AntigenNeuronectinTenascin-CTn-C |
Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Protein Names | Tenascin proteinTn proteinCytotactin proteinGmem proteinGp 150-225 proteinGlioma-Associated-Extracellular Matrix Antigen proteinHexabrachion proteinJi proteinMyotendinous Antigen proteinNeuronectin proteinTenascin-C proteinTn-C proteinTNC proteinHXB protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance