| Host: |
E.coli |
| Applications: |
SDS-PAGE |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Recombinant-Human TCP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: |
Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1mM PMSF, 10% Glycerol |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TCP1 |
| Gene ID: |
6950 |
| Uniprot ID: |
TCPA_HUMAN |
| Immunogen Region: |
1-556aa |
| Accession Number: |
NP_110379 |
| Immunogen: |
Human |
| Immunogen Sequence: |
MEGPLSVFGD RSTGETIRSQ NVMAAASIAN IVKSSLGPVG LDKMLVDDIG DVTITNDGAT ILKLLEVEHP AAKVLCELAD LQDKEVGDGT TSVVIIAAEL LKNADELVKQ KIHPTSVISG YRLACKEAVR YINENLIVNT DELGRDCLIN AAKTSMSSKI IGINGDFFAN MVVDAVLAIK YTDIRGQPRY PVNSVNILKA HGRSQM |
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit AlphaTcp-1-AlphaCct-AlphaChaperonin Containing T-Complex Polypeptide 1 Subunit 1 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytosolCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Protein Names | T-Complex Protein 1 Subunit Alpha proteinTcp-1-Alpha proteinCct-Alpha proteinChaperonin Containing T-Complex Polypeptide 1 Subunit 1 proteinTCP1 proteinCCT1 proteinCCTA protein |
Information sourced from Uniprot.org
