Human TCL1A protein (Recombinant) (No-Tag) (STJP016533)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human TCL1A-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCL1A |
| Gene ID | 8115 |
| Uniprot ID | TCL1A_HUMAN |
| Accession Number | NP_001092195.1 |
| Immunogen | Human |
| Immunogen Region | 1-114aa |
| Immunogen Sequence | MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD |
Additional Info
| Tissue Specificity | Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Protein Names | T-Cell Leukemia/Lymphoma Protein 1a proteinOncogene Tcl-1 proteinOncogene Tcl1 proteinProtein P14 Tcl1 proteinTCL1A proteinTCL1 protein |
Information sourced from Uniprot.org