| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human TBX5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TBX5 |
| Gene ID: | 6910 |
| Uniprot ID: | TBX5_HUMAN |
| Immunogen Region: | Gln43-Lys253 |
| Immunogen: | Homo sapiens (Human) |
| Function | DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif of NPPA promoter. |
| Protein Name | T-Box Transcription Factor Tbx5T-Box Protein 5 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-5578768Reactome: R-HSA-9733709 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And The NucleusAcetylation At Lys-339 Promotes Nuclear Retention |
| Alternative Protein Names | T-Box Transcription Factor Tbx5 proteinT-Box Protein 5 proteinTBX5 protein |
Information sourced from Uniprot.org