Tissue Specificity | Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. |
Post Translational Modifications | Hemoregulatory peptide AcSDKP: AcSDKP is inactivated by ACE, which removes the dipeptide Lys-Pro from its C-terminus. |
Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Hemoregulatory peptide AcSDKP: Potent inhibitor of bone marrow derived stem cell differentiation. Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. |
Protein Name | Thymosin Beta-4T Beta-4Fx Cleaved Into - Hemoregulatory Peptide AcsdkpAc-Ser-Asp-Lys-ProN-Acetyl-SdkpAcsdkpSeraspenide |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | CytoplasmCytoskeleton |
Alternative ELISA Names | Thymosin Beta-4 ELISA kitT Beta-4 ELISA kitFx Cleaved Into - Hemoregulatory Peptide Acsdkp ELISA kitAc-Ser-Asp-Lys-Pro ELISA kitN-Acetyl-Sdkp ELISA kitAcsdkp ELISA kitSeraspenide ELISA kitTMSB4X ELISA kitTB4X ELISA kitTHYB4 ELISA kitTMSB4 ELISA kit |
output | |
Information sourced from Uniprot.org