Human TACTILE/CD96 protein (Recombinant) (C-His&Avi) {Biotin} (STJP019844)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human TACTILE/CD96 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val22-Met503) of Human TACTILE/CD96 (Accession #P40200-2) fused with a C-His&Avi tag at the C-terminus.
General Information
| Short Description | Recombinant-Human TACTILE/CD96-C-His&Avi protein was developed in hek293 cells using the region Val22-Met503. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CD96 |
| Gene ID | 10225 |
| Uniprot ID | TACT_HUMAN |
| Immunogen | Biotinylated Recombinant Human TACTILE/CD96 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val22-Met503) of Human TACTILE/CD96 (Accession #P40200-2) fused with a C-His&Avi tag at the C-terminus. |
| Immunogen Region | Val22-Met503 |
| Immunogen Sequence | VWEKTVNTEENVYATLGSDV NLTCQTQTVGFFVQMQWSKV TNKIDLIAVYHPQYGFYCAY GRPCESLVTFTETPENGSKW TLHLRNMSCSVSGRYECMLV LYPEGIQTKIYNLLIQTHVT ADEWNSNHTIEIEINQTLEI PCFQNSSSKISSEFTYAWSV EDNGTQETLISQNHLISNST LLKDRVKLGTDYRLHLSPVQ IFDDGRKFSCHIRVGPNKIL RSSTTVKVFAKPEIPVIVE |
Additional Info
| Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
| Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
| Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | T-Cell Surface Protein Tactile proteinCell Surface Antigen Cd96 proteinT Cell-Activated Increased Late Expression Protein proteinCd Antigen Cd96 proteinCD96 protein |
Information sourced from Uniprot.org