Human SYN1 protein (Recombinant) (N-His) (STJP004197)

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STJP004197
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SYN1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SYN1
Gene ID: 6853
Uniprot ID: SYN1_HUMAN
Immunogen Region: Gly160-Ile291
Immunogen: Homo sapiens (Human)
Function Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Protein Name Synapsin-1
Brain Protein 4.1
Synapsin I
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-212676
Reactome: R-HSA-9662360
Cellular Localisation Synapse
Golgi Apparatus
Presynapse
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle
Dissociates From Synaptic Vesicles And Redistributes Into The Axon During Action Potential Firing
In A Step That Precedes Fusion Of Vesicles With The Plasma Membrane
Reclusters To Presynapses After The Cessation Of Synaptic Activity
Alternative Protein Names Synapsin-1 protein
Brain Protein 4.1 protein
Synapsin I protein
SYN1 protein

Information sourced from Uniprot.org