Human SYCP3 protein (Recombinant) (N-His) (STJP009666)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SYCP3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SYCP3 |
| Gene ID | 50511 |
| Uniprot ID | SYCP3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys83-Phe236 |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. |
| Protein Name | Synaptonemal Complex Protein 3Scp-3 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeCentromereIt Is Present In Early Unpaired CoresIn The Lateral Domains Of The Synaptonemal Complex And In The Chromosome Cores When They Separate At DiploteneIt Is Found Axial To The Metaphase I Chromosomes And In Association With Pairs Of Sister CentromeresThe Centromere-Associated Protein Becomes Dissociated From The Centromeres At Anaphase Ii And Is Not Found In Mitotic Metaphase Centromeres |
| Alternative Protein Names | Synaptonemal Complex Protein 3 proteinScp-3 proteinSYCP3 proteinSCP3 protein |
Information sourced from Uniprot.org