Human SYCE3 protein (Recombinant) (His-Tag) (STJP017781)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SYCE3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SYCE3 |
| Gene ID | 644186 |
| Uniprot ID | SYCE3_HUMAN |
| Accession Number | NP_001116697 |
| Immunogen | Human |
| Immunogen Region | 1-88aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MDDADPEERN YDNMLKMLSD LNKDLEKLLE EMEKISVQAT WMAYDMVVMR TNPTLAESMR RLEDAFVNCK EEMEKNWQEL LHETKQRL |
Additional Info
| Function | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for the assembly of the central element of the synaptonemal complex during meiosis, via remodeling of SYCP1 lattice structures and promoting recruitment of SYCE2-TEX12 and SYCE1-SIX60S1 complexes. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility and normal testis development. |
| Protein Name | Synaptonemal Complex Central Element Protein 3Testis Highly Expressed Gene 2 ProteinTheg-2 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeColocalizes With Syce1 In The Central Elements |
| Alternative Protein Names | Synaptonemal Complex Central Element Protein 3 proteinTestis Highly Expressed Gene 2 Protein proteinTheg-2 proteinSYCE3 proteinC22orf41 proteinTHEG2 protein |
Information sourced from Uniprot.org