Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018789)

Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018789)

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STJE0018789
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.113ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This SUZ12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SUZ12
Gene ID: 23512
Uniprot ID: SUZ12_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Overexpressed in breast and colon cancer.
Post Translational Modifications Sumoylated, probably by PIAS2.
Function Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Protein Name Polycomb Protein Suz12
Chromatin Precipitated E2f Target 9 Protein
Chet 9 Protein
Joined To Jazf1 Protein
Suppressor Of Zeste 12 Protein Homolog
Database Links Reactome: R-HSA-212300
Reactome: R-HSA-2559580
Reactome: R-HSA-3214841
Reactome: R-HSA-4551638
Reactome: R-HSA-5617472
Reactome: R-HSA-8943724
Reactome: R-HSA-8953750
Reactome: R-HSA-9609690
Reactome: R-HSA-9710421
Cellular Localisation Nucleus
Localizes To Chromatin As Part Of The Prc2 Complex
Alternative ELISA Names Polycomb Protein Suz12 ELISA kit
Chromatin Precipitated E2f Target 9 Protein ELISA kit
Chet 9 Protein ELISA kit
Joined To Jazf1 Protein ELISA kit
Suppressor Of Zeste 12 Protein Homolog ELISA kit
SUZ12 ELISA kit
CHET9 ELISA kit
JJAZ1 ELISA kit
KIAA0160 ELISA kit
output

Information sourced from Uniprot.org

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