Human SUMO3 protein (Recombinant) (C-His) (STJP013380)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SUMO3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM Citrate, 10% Trehalose, 3% Dextran-70, 50mM NaCl, 0.05% Tween 80, pH 3.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | SUMO3 |
| Gene ID | 6612 |
| Uniprot ID | SUMO3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser2-Gly92 |
Additional Info
| Post Translational Modifications | Polymeric chains can be formed through Lys-11 cross-linking. Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function. |
| Function | Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX. |
| Protein Name | Small Ubiquitin-Related Modifier 3Sumo-3Smt3 Homolog 1Sumo-2Ubiquitin-Like Protein Smt3aSmt3a |
| Database Links | Reactome: R-HSA-3065676Reactome: R-HSA-3065678Reactome: R-HSA-3065679Reactome: R-HSA-3108214Reactome: R-HSA-3232118Reactome: R-HSA-3899300Reactome: R-HSA-4090294Reactome: R-HSA-4551638Reactome: R-HSA-4615885Reactome: R-HSA-4755510Reactome: R-HSA-5696395 |
| Cellular Localisation | CytoplasmNucleusPml Body |
| Alternative Protein Names | Small Ubiquitin-Related Modifier 3 proteinSumo-3 proteinSmt3 Homolog 1 proteinSumo-2 proteinUbiquitin-Like Protein Smt3a proteinSmt3a proteinSUMO3 proteinSMT3A proteinSMT3H1 protein |
Information sourced from Uniprot.org