Human SUMF1 protein (Recombinant) (N-His) (STJP005712)

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STJP005712
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SUMF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SUMF1
Gene ID: 285362
Uniprot ID: SUMF1_HUMAN
Immunogen Region: Glu113-Ser356
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. Contains high-mannose-type oligosaccharides.
Function Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.
Protein Name Formylglycine-Generating Enzyme
Fge
C-Alpha-Formylglycine-Generating Enzyme 1
Sulfatase-Modifying Factor 1
Database Links Reactome: R-HSA-1663150
Reactome: R-HSA-9840310
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Protein Names Formylglycine-Generating Enzyme protein
Fge protein
C-Alpha-Formylglycine-Generating Enzyme 1 protein
Sulfatase-Modifying Factor 1 protein
SUMF1 protein
PSEC0152 protein
UNQ3037 protein
PRO9852 protein

Information sourced from Uniprot.org

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