Human SUMF1 protein (Recombinant) (C-His) (STJP013530)

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STJP013530-100
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Short Description :Recombinant-Human SUMF1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:SUMF1
Gene ID:285362
Uniprot ID:SUMF1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ser34-Asp374
Post Translational Modifications N-glycosylated. Contains high-mannose-type oligosaccharides.
Function Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.
Protein Name Formylglycine-Generating Enzyme
Fge
C-Alpha-Formylglycine-Generating Enzyme 1
Sulfatase-Modifying Factor 1
Database Links Reactome: R-HSA-1663150
Reactome: R-HSA-9840310
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Protein Names Formylglycine-Generating Enzyme protein
Fge protein
C-Alpha-Formylglycine-Generating Enzyme 1 protein
Sulfatase-Modifying Factor 1 protein
SUMF1 protein
PSEC0152 protein
UNQ3037 protein
PRO9852 protein

Information sourced from Uniprot.org

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