Human Sulfotransferase 1C4/SULT1C4 protein (Recombinant) (His-Tag) (STJP018217)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Sulfotransferase 1C4/SULT1C4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT1C4 |
| Gene ID | 27233 |
| Uniprot ID | ST1C4_HUMAN |
| Accession Number | NP_006579 |
| Immunogen | Human |
| Immunogen Region | 1-302aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal cord. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Can also sulfonate estrogenic compounds, however, the dietary flavonoids (phytoestrogen) and environmental estrogens, like bisphenol A are better substrates than 17beta-estradiol (E2). Mediates the sulfation of doxorubicin and its analog epirubicin, two antitumor anthracyclines. |
| Protein Name | Sulfotransferase 1c4St1c4Sulfotransferase 1c2Sult1c#2 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Sulfotransferase 1c4 proteinSt1c4 proteinSulfotransferase 1c2 proteinSult1c#2 proteinSULT1C4 proteinSULT1C2 protein |
Information sourced from Uniprot.org