SDS-PAGE gel of recombinant human Substance P TAC1 protein under reducing conditions stained with Coomassie blue

Human Substance P/TAC1 protein (Recombinant) (His-Tag) (STJP017986)

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STJP017986
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Short Description :Recombinant-Human Substance P/TAC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 2M urea
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:TAC1
Gene ID:6863
Uniprot ID:TKN1_HUMAN
Accession Number:NP_003173
Immunogen:Human
Immunogen Region:20-129aa
Immunogen Sequence:EEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALL KALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR
Post Translational Modifications Substance P: The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). Substance P is also cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME).
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Protein Name Protachykinin-1
Ppt Cleaved Into - Substance P - Neurokinin A
Nka
Neuromedin L
Substance K - Neuropeptide K
Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide
Database Links Reactome: R-HSA-380095
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Protein Names Protachykinin-1 protein
Ppt Cleaved Into - Substance P - Neurokinin A protein
Nka protein
Neuromedin L protein
Substance K - Neuropeptide K protein
Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide protein
TAC1 protein
NKA protein
NKNA protein
TAC2 protein

Information sourced from Uniprot.org

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