Human Substance P/TAC1 protein (Recombinant) (His-Tag) (STJP017986)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Substance P/TAC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 2M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAC1 |
| Gene ID | 6863 |
| Uniprot ID | TKN1_HUMAN |
| Accession Number | NP_003173 |
| Immunogen | Human |
| Immunogen Region | 20-129aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Substance P: The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). Substance P is also cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). |
| Function | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. |
| Protein Name | Protachykinin-1Ppt Cleaved Into - Substance P - Neurokinin ANkaNeuromedin LSubstance K - Neuropeptide KNpk - Neuropeptide Gamma - C-Terminal-Flanking Peptide |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Protachykinin-1 proteinPpt Cleaved Into - Substance P - Neurokinin A proteinNka proteinNeuromedin L proteinSubstance K - Neuropeptide K proteinNpk - Neuropeptide Gamma - C-Terminal-Flanking Peptide proteinTAC1 proteinNKA proteinNKNA proteinTAC2 protein |
Information sourced from Uniprot.org