Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human SSB-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | SSB |
Gene ID: | 6741 |
Uniprot ID: | LA_HUMAN |
Immunogen Region: | Asn4-Glu194 |
Immunogen: | Homo sapiens (Human) |
Function | Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. |
Protein Name | Lupus La ProteinLa AutoantigenLa RibonucleoproteinSjoegren Syndrome Type B AntigenSs-B |
Database Links | Reactome: R-HSA-73980Reactome: R-HSA-749476 |
Cellular Localisation | Nucleus |
Alternative Protein Names | Lupus La Protein proteinLa Autoantigen proteinLa RibonucleoproteinSjoegren Syndrome Type B Antigen proteinSs-B proteinSSB protein |
Information sourced from Uniprot.org