| Tissue Specificity | Detected in liver (at protein level). |
| Post Translational Modifications | Ubiquitinated by MARCHF6 in response to high cholesterol levels in intracellular membranes, leading to proteasomal degradation. |
| Function | Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. |
| Protein Name | Squalene MonooxygenaseSqualene EpoxidaseSe |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Microsome MembranePeripheral Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative ELISA Names | Squalene Monooxygenase ELISA kitSqualene Epoxidase ELISA kitSe ELISA kitSQLE ELISA kitERG1 ELISA kit |
| output | |
Information sourced from Uniprot.org