Human SOX15 protein (Recombinant) (N-GST & C-His) (STJP010694)

SKU:
STJP010694
€410.63 - €1,796.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SOX15-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SOX15
Gene ID: 6665
Uniprot ID: SOX15_HUMAN
Immunogen Region: Met53-Asp115
Immunogen: Homo sapiens (Human)
Function Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence. Acts as a transcriptional activator and repressor. Binds synergistically with POU5F1 (OCT3/4) to gene promoters. Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation. Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG. Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity. Regulates transcription of HRC via binding to it proximal enhancer region. Involved in skeletal muscle regeneration. Also plays a role in the development of myogenic precursor cells.
Protein Name Transcription Factor Sox-15
Protein Sox-12
Protein Sox-20
Sry-Box Transcription Factor 15
Cellular Localisation Nucleus
Alternative Protein Names Transcription Factor Sox-15 protein
Protein Sox-12 protein
Protein Sox-20 protein
Sry-Box Transcription Factor 15 protein
SOX15 protein
SOX12 protein
SOX20 protein
SOX26 protein
SOX27 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP011289 Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289) E. coli
STJP009619 Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619) E. coli
STJP007410 Human MYL3 protein (Recombinant) (N-GST & C-His) (STJP007410) E. coli
STJP007465 Human FXYD1 protein (Recombinant) (N-GST & C-His) (STJP007465) E. coli
STJP007755 Human RPS26 protein (Recombinant) (N-GST & C-His) (STJP007755) E. coli

Related Products

!