Human SOST (Sclerostin) Antibody Pair (STJAP00435)
General Information
| Short Description | This SOST antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | SOST |
| Gene ID | 50964 |
| Uniprot ID | SOST_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human SOST protien.Detection Immunogen: Recombinant Human SOST protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
| Protein Name | Sclerostin |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Pair Names | Sclerostin antibody pairSOST antibody pairUNQ2976 antibody pairPRO7455 antibody pairPRO7476 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human SOST (Sclerostin) Antibody Pair (STJAP00435)
This antibody pair detects human Sclerostin (SOST), corresponding to UniProt entry Q9BQB4. Reactivity has been confirmed for human samples only.
Both antibodies are raised in goat and supplied at 0.5 mg/mL. The capture antibody is unconjugated, formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is biotinylated and formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5.
This pair is validated for use in ELISA. No other assay formats are listed for this product.
Both the capture and detection antibodies were raised against recombinant human SOST protein. Both antibodies have been purified by antigen affinity chromatography.
This pair is suitable for use with serum, plasma, and other biological fluids. These are intended for in vitro research use only and are not validated for diagnostic or therapeutic applications.
Both components should be stored at -20 degrees Celsius for long-term storage. Repeated freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.