Human SORBS1 protein (Recombinant) (N-His) (STJP008963)

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STJP008963
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SORBS1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SORBS1
Gene ID: 10580
Uniprot ID: SRBS1_HUMAN
Immunogen Region: Thr773-Pro929
Immunogen: Homo sapiens (Human)
Post Translational Modifications O-glycosylated.
Function Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
Protein Name Sorbin And Sh3 Domain-Containing Protein 1
Ponsin
Sh3 Domain Protein 5
Sh3p12
C-Cbl-Associated Protein
Cap
Database Links Reactome: R-HSA-445355
Cellular Localisation Cell Junction
Adherens Junction
Cell Membrane
Cytoplasm
Cytoskeleton
Focal Adhesion
Nucleus
Nucleus Matrix
Colocalizes With The Ten-1 Icd Form Of Tenm1 In The Nucleus
Colocalizes With Actin Stress Fibers
Also Detected At The Plasma Membrane And In Neuronal Intranuclear Inclusions
Colocalized With Pxn At Focal Adhesions During Myogenic Differentiation
Alternative Protein Names Sorbin And Sh3 Domain-Containing Protein 1 protein
Ponsin protein
Sh3 Domain Protein 5 protein
Sh3p12 protein
C-Cbl-Associated Protein protein
Cap protein
SORBS1 protein
KIAA0894 protein
KIAA1296 protein
SH3D5 protein

Information sourced from Uniprot.org

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