| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human GH1 at 2 Mu g/mL (100 Mu L/well) can bind Human GHR with a linear range of 0.1-19.4 ng/mL. |
| Gene Symbol: | GH1 |
| Gene ID: | 2688 |
| Uniprot ID: | SOMA_HUMAN |
| Immunogen Region: | Phe27-Phe217 |
| Immunogen: | Recombinant Human Somatotropin/GH-N/GH1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Phe27-Phe217) of human GH (Accession #NP_000506.2) fused with an initial Met at the N-terminus and a 6×His |
| Immunogen Sequence: | TPVVRKGRCSCISTNQGTIH LQSLKDLKQFAPSPSCEKIE IIATLKNGVQTCLNPDSADV KELIKKWEKQVSQKKKQKNG KKHQKKKVLKVRKSQRSRQK KTT |
| Function | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. |
| Protein Name | Somatotropin Growth Hormone Gh Gh-N Growth Hormone 1 Pituitary Growth Hormone |
| Database Links | Reactome: R-HSA-1170546 Reactome: R-HSA-422085 Reactome: R-HSA-982772 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Somatotropin protein Growth Hormone protein Gh protein Gh-N protein Growth Hormone 1 protein Pituitary Growth Hormone protein GH1 protein |
Information sourced from Uniprot.org
