Human Somatotropin/GH-N/GH1 protein (Recombinant) (No tag) (STJP002901)

SKU:
STJP002901

Current Stock:
Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human GH1 at 2 Mu g/mL (100 Mu L/well) can bind Human GHR with a linear range of 0.1-19.4 ng/mL.
Gene Symbol: GH1
Gene ID: 2688
Uniprot ID: SOMA_HUMAN
Immunogen Region: Phe27-Phe217
Immunogen: Recombinant Human Somatotropin/GH-N/GH1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Phe27-Phe217) of human GH (Accession #NP_000506.2) fused with an initial Met at the N-terminus and a 6×His
Immunogen Sequence: TPVVRKGRCSCISTNQGTIH LQSLKDLKQFAPSPSCEKIE IIATLKNGVQTCLNPDSADV KELIKKWEKQVSQKKKQKNG KKHQKKKVLKVRKSQRSRQK KTT
Function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Protein Name Somatotropin
Growth Hormone
Gh
Gh-N
Growth Hormone 1
Pituitary Growth Hormone
Database Links Reactome: R-HSA-1170546
Reactome: R-HSA-422085
Reactome: R-HSA-982772
Cellular Localisation Secreted
Alternative Protein Names Somatotropin protein
Growth Hormone protein
Gh protein
Gh-N protein
Growth Hormone 1 protein
Pituitary Growth Hormone protein
GH1 protein

Information sourced from Uniprot.org

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