Human SNAT1 (Sodium Coupled Neutral Amino Acid Transporter 1) Sandwich ELISA Kit (STJE0012248)
SPECIFICATIONS
General Information
| Short Description | This SNAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.055ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | SLC38A1 |
| Gene ID | 81539 |
| Uniprot ID | S38A1_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. Highly expressed in cytotrophoblast cells from term placenta. |
| Post Translational Modifications | N-glycosylation plays an important role in the L-glutamine transport. |
| Function | Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis. May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Symporter 1Amino Acid Transporter A1N-System Amino Acid Transporter 2Solute Carrier Family 38 Member 1System A Amino Acid Transporter 1System N Amino Acid Transporter 1 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinRestricted To The Somatodendritic Compartment Of NeuronsFound In The Cellular Processes Of Neurons In The Developing Brain |
| Alternative ELISA Names | Sodium-Coupled Neutral Amino Acid Symporter 1 ELISA kitAmino Acid Transporter A1 ELISA kitN-System Amino Acid Transporter 2 ELISA kitSolute Carrier Family 38 Member 1 ELISA kitSystem A Amino Acid Transporter 1 ELISA kitSystem N Amino Acid Transporter 1 ELISA kitSLC38A1 ELISA kitATA1 ELISA kitNAT2 ELISA kitSAT1 ELISA kitSNAT1 ELISA kit |
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Information sourced from Uniprot.org