Human SMYD3 protein (Recombinant) (N-His) (STJP008214)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP008214
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General Information

Short DescriptionRecombinant-Human SMYD3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolSMYD3
Gene ID64754
Uniprot IDSMYD3_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Ser428

Additional Info

Function Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys-5' of histone H4. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.
Protein Name Histone-Lysine N-Methyltransferase Smyd3
Set And Mynd Domain-Containing Protein 3
Zinc Finger Mynd Domain-Containing Protein 1
Database Links Reactome: R-HSA-3214841
Cellular Localisation Cytoplasm
Nucleus
Mainly Cytoplasmic When Cells Are Arrested At G0/G1
Accumulates In The Nucleus At S Phase And G2/M
Alternative Protein Names Histone-Lysine N-Methyltransferase Smyd3 protein
Set And Mynd Domain-Containing Protein 3 protein
Zinc Finger Mynd Domain-Containing Protein 1 protein
SMYD3 protein
ZMYND1 protein
ZNFN3A1 protein

Information sourced from Uniprot.org

Citations

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