Human SMOX protein (Recombinant) (N-His) (STJP006091)

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STJP006091
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SMOX-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SMOX
Gene ID: 54498
Uniprot ID: SMOX_HUMAN
Immunogen Region: Met1-Gln165
Immunogen: Homo sapiens (Human)
Function Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Protein Name Spermine Oxidase
Polyamine Oxidase 1
Pao-1
Paoh1
Database Links Reactome: R-HSA-141334 Q9NWM0-3
Reactome: R-HSA-351200 Q9NWM0-3
Cellular Localisation Isoform 1: Cytoplasm
Nucleus
Isoform 4: Cytoplasm
Isoform 6: Cytoplasm
Alternative Protein Names Spermine Oxidase protein
Polyamine Oxidase 1 protein
Pao-1 protein
Paoh1 protein
SMOX protein
C20orf16 protein
SMO protein
UNQ3039 protein
PRO9854 protein

Information sourced from Uniprot.org