Human SLURP1 protein (Recombinant) (N-GST & C-His) (STJP011368)

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STJP011368
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLURP1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLURP1
Gene ID: 57152
Uniprot ID: SLUR1_HUMAN
Immunogen Region: Leu23-Leu103
Immunogen: Homo sapiens (Human)
Function Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation.
Protein Name Secreted Ly-6/Upar-Related Protein 1
Slurp-1
Ars Component B
Ars(Component B-81/S
Anti-Neoplastic Urinary Protein
Anup
Cellular Localisation Secreted
Alternative Protein Names Secreted Ly-6/Upar-Related Protein 1 protein
Slurp-1 protein
Ars Component B protein
Ars(Component B-81/S protein
Anti-Neoplastic Urinary Protein protein
Anup protein
SLURP1 protein
ARS protein

Information sourced from Uniprot.org

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