| Short Description : | This SLN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.121ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | SLN |
| Gene ID: | 6588 |
| Uniprot ID: | SARCO_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Reversibly inhibits the activity of ATP2A1/SERCA1 and ATP2A2/SERCA2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Also inhibits the activity of ATP2A3/SERCA3. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis. |
| Protein Name | Sarcolipin |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | Sarcoplasmic Reticulum MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative ELISA Names | Sarcolipin ELISA kitSLN ELISA kit |
| output |
Information sourced from Uniprot.org
