Human SLC1A7 protein (Recombinant) (N-His) (STJP003147)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC1A7-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SLC1A7 |
| Gene ID | 6512 |
| Uniprot ID | EAA5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His115-Thr216 |
Additional Info
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina. |
| Protein Name | Excitatory Amino Acid Transporter 5Retinal Glutamate TransporterSolute Carrier Family 1 Member 7 |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Photoreceptor Inner Segment MembraneMulti-Pass Membrane ProteinSynaptic Cell MembraneLocated In Both Cone And Rod Photoreceptor Terminals And In Axon Terminals Of Rod Bipolar Cells |
| Alternative Protein Names | Excitatory Amino Acid Transporter 5 proteinRetinal Glutamate Transporter proteinSolute Carrier Family 1 Member 7 proteinSLC1A7 proteinEAAT5 protein |
Information sourced from Uniprot.org