Human SLC1A7 protein (Recombinant) (N-His) (STJP003147)

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STJP003147
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC1A7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC1A7
Gene ID: 6512
Uniprot ID: EAA5_HUMAN
Immunogen Region: His115-Thr216
Immunogen: Homo sapiens (Human)
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina.
Protein Name Excitatory Amino Acid Transporter 5
Retinal Glutamate Transporter
Solute Carrier Family 1 Member 7
Database Links Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Photoreceptor Inner Segment Membrane
Multi-Pass Membrane Protein
Synaptic Cell Membrane
Located In Both Cone And Rod Photoreceptor Terminals And In Axon Terminals Of Rod Bipolar Cells
Alternative Protein Names Excitatory Amino Acid Transporter 5 protein
Retinal Glutamate Transporter protein
Solute Carrier Family 1 Member 7 protein
SLC1A7 protein
EAAT5 protein

Information sourced from Uniprot.org

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