Human SLC1A2 protein (Recombinant) (N-GST) (STJP004730)

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STJP004730
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC1A2-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC1A2
Gene ID: 6506
Uniprot ID: EAA2_HUMAN
Immunogen Region: Pro460-Lys574
Immunogen: Homo sapiens (Human)
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 2
Glutamate/Aspartate Transporter Ii
Sodium-Dependent Glutamate/Aspartate Transporter 2
Solute Carrier Family 1 Member 2
Database Links Reactome: R-HSA-210455
Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Excitatory Amino Acid Transporter 2 protein
Glutamate/Aspartate Transporter Ii protein
Sodium-Dependent Glutamate/Aspartate Transporter 2 protein
Solute Carrier Family 1 Member 2 protein
SLC1A2 protein
EAAT2 protein
GLT1 protein

Information sourced from Uniprot.org