Human SLC12A2 protein (Recombinant) (N-His) (STJP010915)

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STJP010915
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC12A2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC12A2
Gene ID: 6558
Uniprot ID: S12A2_HUMAN
Immunogen Region: Asn1002-Ser1212
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated at Thr-203, Thr-207 and Thr-212 by OXSR1/OSR1 and STK39/SPAK downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4), promoting its activity.
Function Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume.
Protein Name Solute Carrier Family 12 Member 2
Basolateral Na-K-Cl Symporter
Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2
Bsc2
Na-K-2cl Cotransporter 1
Hnkcc1
Database Links Reactome: R-HSA-426117
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Solute Carrier Family 12 Member 2 protein
Basolateral Na-K-Cl Symporter protein
Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2 protein
Bsc2 protein
Na-K-2cl Cotransporter 1 protein
Hnkcc1 protein
SLC12A2 protein
NKCC1 protein

Information sourced from Uniprot.org

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