Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human SIRP gamma/CD172g-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: | SIRPG |
Gene ID: | 55423 |
Uniprot ID: | SIRPG_HUMAN |
Immunogen Region: | Glu29-Pro360 |
Immunogen: | DNA sequence encoding Human SIRP gamma/CD172g including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
Protein Name | Signal-Regulatory Protein GammaSirp-GammaCd172 Antigen-Like Family Member BSignal-Regulatory Protein Beta-2Sirp-B2Sirp-Beta-2Cd Antigen Cd172g |
Database Links | Reactome: R-HSA-202733Reactome: R-HSA-391160 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Signal-Regulatory Protein Gamma proteinSirp-Gamma proteinCd172 Antigen-Like Family Member B proteinSignal-Regulatory Protein Beta-2 proteinSirp-B2 proteinSirp-Beta-2 proteinCd Antigen Cd172g proteinSIRPG proteinSIRPB2 protein |
Information sourced from Uniprot.org