• Biotinylated Human SIRP Beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human SIRP Beta is greater than 95% as determined by SEC-HPLC.

Human SIRP Beta/CD172b protein (Recombinant) (C-His-Avi) {Biotin} (STJP001609)

SKU:
STJP001609

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SIRP Beta/CD172b-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: SIRPB1
Gene ID: 10326
Uniprot ID: SIRB1_HUMAN
Immunogen Region: Glu30-Ala369
Immunogen: DNA sequence encoding Human SIRP Beta/CD172b including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications N-glycosylated.
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Protein Name Signal-Regulatory Protein Beta-1
Sirp-Beta-1
Cd172 Antigen-Like Family Member B
Cd Antigen Cd172b
Database Links Reactome: R-HSA-2172127
Reactome: R-HSA-391160
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Signal-Regulatory Protein Beta-1 protein
Sirp-Beta-1 protein
Cd172 Antigen-Like Family Member B protein
Cd Antigen Cd172b protein
SIRPB1 protein

Information sourced from Uniprot.org

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