Biotinylated Human SIRP Beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Human SIRP Beta/CD172b protein (Recombinant) (C-His-Avi) {Biotin} (STJP001609)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
HostHEK293
ConjugationBiotin
ImmunogenDNA sequence encoding Human SIRP Beta/CD172b including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
STJP001609
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General Information

Short DescriptionRecombinant-Human SIRP Beta/CD172b-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
HostHEK293
NoteSTRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationBiotin
Dilution RangeUpon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
FormulationLyophilised from 0.2 ยตm filtered PBS solution pH7.4.
Storage InstructionThe lyophilized protein is stable for at least 1 year from date of receipt at-20ยฐC.
EndotoxinEndotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ยตg (1EU/ยตg).

Target Information

Gene SymbolSIRPB1
Gene ID10326
Uniprot IDSIRB1_HUMAN
ImmunogenDNA sequence encoding Human SIRP Beta/CD172b including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Immunogen RegionGlu30-Ala369

Additional Info

Post Translational Modifications N-glycosylated.
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Protein Name Signal-Regulatory Protein Beta-1
Sirp-Beta-1
Cd172 Antigen-Like Family Member B
Cd Antigen Cd172b
Database Links Reactome: R-HSA-2172127
Reactome: R-HSA-391160
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Signal-Regulatory Protein Beta-1 protein
Sirp-Beta-1 protein
Cd172 Antigen-Like Family Member B protein
Cd Antigen Cd172b protein
SIRPB1 protein

Information sourced from Uniprot.org

Citations

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