Human SIAE protein (Recombinant) (N-GST) (STJP006007)

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STJP006007
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SIAE-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SIAE
Gene ID: 54414
Uniprot ID: SIAE_HUMAN
Immunogen Region: Ala22-Pro244
Immunogen: Homo sapiens (Human)
Function Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity.
Protein Name Sialate O-Acetylesterase
Siae
H-Lse
Sialic Acid-Specific 9-O-Acetylesterase
Cellular Localisation Isoform 1: Lysosome
Isoform 2: Cytoplasm
Alternative Protein Names Sialate O-Acetylesterase protein
Siae protein
H-Lse protein
Sialic Acid-Specific 9-O-Acetylesterase protein
SIAE protein
YSG2 protein

Information sourced from Uniprot.org

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