Function | Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity. |
Protein Name | Sialate O-AcetylesteraseSiaeH-LseSialic Acid-Specific 9-O-Acetylesterase |
Cellular Localisation | Isoform 1: LysosomeIsoform 2: Cytoplasm |
Alternative Protein Names | Sialate O-Acetylesterase proteinSiae proteinH-Lse proteinSialic Acid-Specific 9-O-Acetylesterase proteinSIAE proteinYSG2 protein |
Information sourced from Uniprot.org