Human SIAE protein (Recombinant) (C-His) (STJP013582)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SIAE-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | SIAE |
| Gene ID | 54414 |
| Uniprot ID | SIAE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile24-Lys523 |
Additional Info
| Function | Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity. |
| Protein Name | Sialate O-AcetylesteraseSiaeH-LseSialic Acid-Specific 9-O-Acetylesterase |
| Database Links | |
| Cellular Localisation | Isoform 1: LysosomeIsoform 2: Cytoplasm |
| Alternative Protein Names | Sialate O-Acetylesterase proteinSiae proteinH-Lse proteinSialic Acid-Specific 9-O-Acetylesterase proteinSIAE proteinYSG2 protein |
Information sourced from Uniprot.org