Human SH3BP5 protein (Recombinant) (N-His) (STJP008943)

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STJP008943
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SH3BP5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SH3BP5
Gene ID: 9467
Uniprot ID: 3BP5_HUMAN
Immunogen Region: Ser10-Glu276
Immunogen: Homo sapiens (Human)
Function Functions as a guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Protein Name Sh3 Domain-Binding Protein 5
Sh3bp-5
Sh3 Domain-Binding Protein That Preferentially Associates With Btk
Cellular Localisation Cytoplasmic Vesicle Membrane
Peripheral Membrane Protein
Mitochondrion
Colocalizes With Rab11a On Cytoplasmic Vesicle Membranes
Alternative Protein Names Sh3 Domain-Binding Protein 5 protein
Sh3bp-5 protein
Sh3 Domain-Binding Protein That Preferentially Associates With Btk protein
SH3BP5 protein
SAB protein

Information sourced from Uniprot.org

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