Human sFRP-5/SFRP5 protein (Recombinant) (His-Tag) (STJP019054)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human sFRP-5/SFRP5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SFRP5 |
| Gene ID | 6425 |
| Uniprot ID | SFRP5_HUMAN |
| Accession Number | NP_003006 |
| Immunogen | Human |
| Immunogen Region | 30-317aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. |
| Protein Name | Secreted Frizzled-Related Protein 5Sfrp-5Frizzled-Related Protein 1bFrp-1bSecreted Apoptosis-Related Protein 3Sarp-3 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secreted Frizzled-Related Protein 5 proteinSfrp-5 proteinFrizzled-Related Protein 1b proteinFrp-1b proteinSecreted Apoptosis-Related Protein 3 proteinSarp-3 proteinSFRP5 proteinFRP1B proteinSARP3 protein |
Information sourced from Uniprot.org