Human sFRP-2/SFRP2 protein (Recombinant) (His-Tag) (STJP018705)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human sFRP-2/SFRP2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SFRP2 |
| Gene ID | 6423 |
| Uniprot ID | SFRP2_HUMAN |
| Accession Number | NP_003004 |
| Immunogen | Human |
| Immunogen Region | 20-295aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSARGLFLF GQPDFSYKRS NCKPIPVNLQ LCHGIEYQNM RLPNLLGHET MKEVLEQAGA WIPLVMKQCH PDTKKFLCSL FAPVCLDDLD ETIQPCHSLC VQVKDRCAPV MSAFGFPWPD MLECDRFPQD NDLCIPLASS DHLLPATEEA PKVCEACKNK NDDDNDIMET LCKNDFALKI KVKEITYINR DTKIILETKS KTIYKLNG |
Additional Info
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Protein Name | Secreted Frizzled-Related Protein 2Frp-2Sfrp-2Secreted Apoptosis-Related Protein 1Sarp-1 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secreted Frizzled-Related Protein 2 proteinFrp-2 proteinSfrp-2 proteinSecreted Apoptosis-Related Protein 1 proteinSarp-1 proteinSFRP2 proteinFRP2 proteinSARP1 proteinFKSG12 proteinUNQ361 proteinPRO697 protein |
Information sourced from Uniprot.org