SDS-PAGE gel of recombinant human SF20 MYDGF protein 3µg under reducing conditions Coomassie blue stain

Human SF20/MYDGF protein (Recombinant) (His-Tag) (STJP019757)

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STJP019757
£110.50 - £535.50
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Short Description :Recombinant-Human SF20/MYDGF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:MYDGF
Gene ID:56005
Uniprot ID:MYDGF_HUMAN
Accession Number:NP_061980
Immunogen:Human
Immunogen Region:33-173aa
Immunogen Sequence:SEPTTVAFD VRPGGVVHSF SHNVGPGDKY TCMFTYASQG GTNEQWQMSL GTSEDHQHFT CTIWRPQGKS YLYFTQFKAE VRGAEIEYAM AYSKAAFERE SDVPLKTEEF EVTKTAVAHR PGAFKAELSK LVIVAKASRT EL
Tissue Specificity Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Protein Name Myeloid-Derived Growth Factor
Mydgf
Database Links Reactome: R-HSA-381038
Cellular Localisation Secreted
Endoplasmic Reticulum-Golgi Intermediate Compartment
Endoplasmic Reticulum
Golgi Apparatus
The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Protein Names Myeloid-Derived Growth Factor protein
Mydgf protein
MYDGF protein
C19orf10 protein

Information sourced from Uniprot.org

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