| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.056ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This SESN3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | SESN3 |
| Gene ID: | 143686 |
| Uniprot ID: | SESN3_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein. |
| Protein Name | Sestrin-3 |
| Database Links | Reactome: R-HSA-5628897 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Sestrin-3 ELISA kitSESN3 ELISA kitSEST3 ELISA kit |
| output |
Information sourced from Uniprot.org