Human SESN3 (Sestrin 3) Sandwich ELISA Kit (STJE0012113)

Human SESN3 (Sestrin 3) Sandwich ELISA Kit (STJE0012113)

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STJE0012113
$628.43 - $859.28
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This SESN3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SESN3
Gene ID: 143686
Uniprot ID: SESN3_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed.
Post Translational Modifications
Function May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein.
Protein Name Sestrin-3
Database Links Reactome: R-HSA-5628897
Cellular Localisation Cytoplasm
Alternative ELISA Names Sestrin-3 ELISA kit
SESN3 ELISA kit
SEST3 ELISA kit
output

Information sourced from Uniprot.org

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