Human SERTAD1 protein (Recombinant) (His-Tag) (STJP017747)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SERTAD1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERTAD1 |
| Gene ID | 29950 |
| Uniprot ID | SRTD1_HUMAN |
| Accession Number | NP_037508.2 |
| Immunogen | Human |
| Immunogen Region | 1-236aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Polyubiquitinated, which promotes proteasomal degradation. |
| Function | Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A. |
| Protein Name | Serta Domain-Containing Protein 1Cdk4-Binding Protein P34sei1Sei-1P34(Sei-1Transcriptional Regulator Interacting With The Phd-Bromodomain 1Trip-Br1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Serta Domain-Containing Protein 1 proteinCdk4-Binding Protein P34sei1 proteinSei-1 proteinP34(Sei-1 proteinTranscriptional Regulator Interacting With The Phd-Bromodomain 1 proteinTrip-Br1 proteinSERTAD1 proteinSEI1 proteinTRIPBR1 protein |
Information sourced from Uniprot.org