| Tissue Specificity | Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). |
| Function | May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
| Protein Name | Serpin B3Protein T4-ASquamous Cell Carcinoma Antigen 1Scca-1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmSeems To Also Be Secreted In Plasma By Cancerous Cells But At A Low Level |
| Alternative Antibody Pair Names | Serpin B3 antibody pairProtein T4-A antibody pairSquamous Cell Carcinoma Antigen 1 antibody pairScca-1 antibody pairSERPINB3 antibody pairSCCA antibody pairSCCA1 antibody pair |
Information sourced from Uniprot.org