Human SERPINA6 protein (Recombinant-Active) (C-His) (STJP011822)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human SERPINA6-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. When Cortisol-BSA Conjugate is Immobilised at 5 Mu g/mL, 100 Mu L/well, recombinant human SERPINA6 binds with an ED50 of 1.5-7.5 Mu g/mL. |
Target Information
| Gene Symbol | SERPINA6 |
| Gene ID | 866 |
| Uniprot ID | CBG_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met23-Val405 |
Additional Info
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Corticosteroid-Binding Globulin proteinCbg proteinSerpin A6 proteinTranscortin proteinSERPINA6 proteinCBG protein |
Information sourced from Uniprot.org