• Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)
  • Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)
  • Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)
  • Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)

Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)

SKU:
STJP001220-20

£168.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Serpin D1/Heparin cofactor 2-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 50mM TRIS, 150mM NaCl, pH7.5. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its ability to inhibit Recombinant Human Coagulation Factor II/Thrombin cleavage of a fluorogenic peptide substrate Boc-VPR-AMC. The IC50 value is
Gene Symbol: SERPIND1
Gene ID: 3053
Uniprot ID: HEP2_HUMAN
Immunogen: Recombinant Human Serpin D1/Heparin cofactor 2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly20-Ser499) of human Serpin D1/Heparin Cofactor II (Accession #NP_000176.2.) fused with a 6×His tag
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Protein Name Heparin Cofactor 2
Heparin Cofactor Ii
Hc-Ii
Protease Inhibitor Leuserpin-2
Hls2
Serpin D1
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-140875
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Alternative Protein Names Heparin Cofactor 2 protein
Heparin Cofactor Ii protein
Hc-Ii protein
Protease Inhibitor Leuserpin-2 protein
Hls2 protein
Serpin D1 protein
SERPIND1 protein
HCF2 protein

Information sourced from Uniprot.org

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